戊型肝炎急性期和恢复期患者外周血中细胞因

文章来源:乙型病毒性肝炎   发布时间:2016-12-7 18:55:04   点击数:
  

Abstract

Background:HepatitisEisamajorpublichealthprobleminthedevelopingcountries.PathogenesisofhepatitisEvirus(HEV)infectionispoorlyunderstood.

Methods:Thiscase-controlstudyincludedHepatitisEpatients(46acuteand78recovered),9withpriorexposuretoHEVand71anti-HEVnegativehealthycontrols.HEVinducedCTLresponsebyElispot,cytokines/chemokinesquantitationbyMilliplexassayandperipheralCD4+CD8+Tcellfrequenciesbyflowcytometrywereassessed.

Results:Amongthepatientcategories,HEVspecificIFN-cresponsesasrecordedbyElispotwere







































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